Jin Hyup Lee Selected Research

oxalomalic acid

4/2019	Oxalomalate suppresses metastatic melanoma through IDH-targeted stress response to ROS.
3/2019	Oxalomalate reduces tumor progression in melanoma via ROS-dependent proapoptotic and antiangiogenic effects.
12/2016	Oxalomalate reduces expression and secretion of vascular endothelial growth factor in the retinal pigment epithelium and inhibits angiogenesis: Implications for age-related macular degeneration.

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Jin Hyup Lee Research Topics

Disease

14	Neoplasms (Cancer) 01/2020 - 05/2005
10	Inflammation (Inflammations) 01/2022 - 01/2017
5	Lung Injury 01/2022 - 01/2017
5	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 09/2008
4	Colitis 03/2019 - 10/2017
3	Colorectal Neoplasms (Colorectal Cancer) 05/2019 - 10/2017
3	Melanoma (Melanoma, Malignant) 04/2019 - 08/2014
2	Non-alcoholic Fatty Liver Disease 01/2021 - 05/2018
2	Diarrhea 01/2020 - 11/2018
2	Fatty Liver 01/2020 - 04/2019
2	Liver Failure 01/2020 - 01/2019
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 01/2020 - 04/2019
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2019 - 05/2018
2	Cardiovascular Diseases (Cardiovascular Disease) 07/2018 - 01/2018
2	Cardiomegaly (Heart Hypertrophy) 01/2018 - 03/2015
1	Atherosclerosis 07/2022
1	Disease Progression 07/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Body Weight (Weight, Body) 09/2020
1	Colonic Neoplasms (Colon Cancer) 09/2020
1	Clostridium Infections 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2020
1	Necrosis 01/2020
1	Bone Resorption 12/2019
1	Neoplasm Metastasis (Metastasis) 04/2019
1	Hypoxia (Hypoxemia) 03/2019
1	Skin Neoplasms (Skin Cancer) 03/2019
1	Hypercholesterolemia 11/2018
1	Acute Liver Failure (Fulminant Hepatic Failure) 11/2018
1	Wounds and Injuries (Trauma) 07/2018
1	Metabolic Diseases (Metabolic Disease) 05/2018
1	Hyperglycemia 01/2018
1	Lung Neoplasms (Lung Cancer) 01/2018
1	Hypertrophy 01/2018
1	Hypertension (High Blood Pressure) 07/2017
1	Lewis Lung Carcinoma 01/2017
1	Lung Diseases (Lung Disease) 01/2017
1	Acute Lung Injury 01/2017
1	Pathologic Neovascularization 12/2016
1	Macular Degeneration (Age-Related Maculopathy) 12/2016
1	Choroidal Neovascularization 12/2016
1	Obesity 10/2016
1	Insulin Resistance 10/2016

Drug/Important Bio-Agent (IBA)

12	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2019 - 08/2014
5	Acrolein (Aqualin)IBA 07/2022 - 01/2017
5	EnzymesIBA 01/2020 - 09/2008
4	FructoseIBA 01/2021 - 01/2018
4	Dextrans (Dextran)FDA Link 03/2019 - 10/2017
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 03/2019 - 10/2017
4	Pharmaceutical PreparationsIBA 03/2019 - 01/2007
3	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2018
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2018
3	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 07/2018
3	oxalomalic acidIBA 04/2019 - 12/2016
3	AntioxidantsIBA 07/2018 - 09/2008
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 05/2018 - 08/2014
3	naringinIBA 01/2018 - 01/2018
2	Environmental Pollutants (Pollutants, Environmental)IBA 07/2022 - 12/2020
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 11/2018
2	LipopolysaccharidesIBA 04/2019 - 01/2018
2	Therapeutic UsesIBA 03/2019 - 04/2007
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 03/2019 - 12/2016
2	Proteins (Proteins, Gene)FDA Link 05/2018 - 10/2016
2	Fatty Acids (Saturated Fatty Acids)IBA 05/2018 - 01/2015
2	NADP (NADPH)IBA 05/2018 - 08/2014
2	Small Interfering RNA (siRNA)IBA 01/2017 - 04/2007
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2013 - 06/2011
2	DNA (Deoxyribonucleic Acid)IBA 06/2011 - 01/2007
2	CryptochromesIBA 06/2011 - 02/2009
2	AntigensIBA 01/2007 - 05/2004
2	VaccinesIBA 05/2005 - 05/2004
1	AminesIBA 09/2020
1	2- amino- 1- methyl- 6- phenylimidazo(4,5- b)pyridineIBA 09/2020
1	TrehaloseIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2020
1	pelargonidinIBA 01/2020
1	erastinIBA 01/2020
1	CarcinogensIBA 10/2019
1	SilymarinIBA 04/2019
1	Matrix Metalloproteinases (MMPs)IBA 04/2019
1	Biological ProductsIBA 03/2019
1	Glutathione (Reduced Glutathione)IBA 01/2019
1	CytokinesIBA 11/2018
1	antiarrhythmic peptide (AAP)IBA 11/2018
1	CholesterolIBA 11/2018
1	Bile Acids and Salts (Bile Acids)IBA 11/2018
1	Mitogen-Activated Protein KinasesIBA 11/2018
1	PolyphenolsIBA 07/2018
1	Chlorogenic AcidIBA 07/2018
1	Insulin (Novolin)FDA Link 01/2018
1	Acetylcysteine (Siran)FDA LinkGeneric 10/2017
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 07/2017
1	Phosphotransferases (Kinase)IBA 04/2017
1	fibroblast growth factor 21IBA 04/2017

Therapy/Procedure

4	Therapeutics 04/2019 - 08/2014
3	Drug Therapy (Chemotherapy) 01/2015 - 01/2007
2	Immunotherapy 01/2007 - 08/2006
1	Radiotherapy 05/2019
1	Oral Administration 11/2018
1	Chemoprevention 10/2017